編輯：劉夏泱 陳盈
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必備先修課程
這門課程沒有正式的必備先修課程，但應瞭解中學水準的生物學和化學（特別是熟悉化學結構的基本知識）。 課本 Freeman, Scott.《生物科學》，Upper Saddle River, NJ: Prentice Hall, 2002. ISBN: 0130819239。 Spencer, Charlotte A.《遺傳的證詞：法醫DNA壓型指導》，Upper Saddle River, NJ: Pearson/Prentice Hall, 2004. ISBN: 013142338X。 複習/實習課程 希望每週都參加。每週兩次，每次50分鐘。 輔導員 對於所有希望就課程內容得到額外幫助的學生，輔導員將提供一次性或經常性的免費輔導。 志願實驗 這個學期，我們再次提供志願實驗，作為課程7.012中一個令人興奮的組成部分。 實驗的目的是給你接觸有機體、實驗設備、技術和分子生物學家的思考方式的實踐經驗。你有機會來做自身的實驗，以及有機會從不同的角度來學習課堂上提出的概念。實驗包括： 分離你自身的DNA
產生和發現酵母突變體
進行酵母突變體的基因治療
實現酵母的雜交
檢測日常生活中的致癌物質
作業 該課程有6個習題集。在這六個要評分的習題集中，最低分的一個會在計算期末成績時被去掉（參看下 文）。習題7是最後一個習題集，將不評分，然而，期末考試將涉及這個習題集的內容。雖然可以對習題進行一般性的討論，但是共用答案將破壞我們對班中所有學 生的信任，我們要求每一個人都做出自己的答案。抄襲習題集答案或允許答案被抄襲的學生，所有習題可能得0分（這樣將失去20%的成績）。 完成的習題集必須在到期日或到期時間內，放到木車中相應的助教信箱中。 注意：不接受遲交的習題集，不按時交作業將得0分。 測驗 本課程將有三次測驗和一次期末考試。測驗將在學期期間進行，一次綜合期末考試（相當2次測驗）將在最後一週進行。 每一次學期測驗將在至少兩個地方舉行，日期在教學大綱中列出。課室的分配見測驗通知。5次考試中 （3次測驗加上相當2次測驗的期末考試）的最低成績將在計算總成績時被去除。因為我們去除了最低分，將沒有理由進行補考或者替代衝突的考試。如果你錯過了 學期測驗，這次成績將被去除。 期末考試是三個小時的綜合考試，內容將涵蓋整個課程。期末考試的成績將被二等分，在計算成績時每一 半作為一次測驗成績計算。因為期末考試代表了5次測驗成績的2次，所以你必須參加，否則將失去成績的百分之二十。如果你期末考試的分數是你最低的分數，則 二等分中的一個將被去除。 期末考試的的日期、時間和地點一經決定後便立即公佈。如有合理的考試衝突，將由註冊處另行安排一次期末考試。 在每一次測驗之前將有測驗復習課－復習課的日期、地點和時間將在學期中公佈。 在學期結束時還未被同學領走的測驗、考試或習題將被銷毀。 成績
Prerequisites There are no formal prerequisites for this course, but we do presuppose high school-level biology and chemistry (especially familiarity with the fundamental aspects of chemical structure). Text Freeman, Scott. Biological Science. Upper Saddle River, NJ: Prentice Hall, 2002. ISBN: 0130819239. Spencer, Charlotte A. Genetic Testimony: a Guide to Forensic DNA Profiling. Upper Saddle River, NJ: Pearson/Prentice Hall, 2004. ISBN: 013142338X. Recitations Regular weekly attendance is expected. Each recitation section meets twice per week for 50 minutes. Tutors Tutors are available at no charge for all students who wish to have extra help with the course material, either on a one-time or on a regular basis. Voluntary Laboratory This semester is the second time we are offering a voluntary lab component as an exciting addition to 7.012. The purpose of the labs is to give you a hands-on experience with the organisms, equipment, techniques, and thought process used by molecular biologists. You will have the opportunity to do experiments for yourselves, and a chance to learn the concepts that are addressed in lecture and section from a different angle. Experiments will include: Isolating your own DNA
Generating and Finding Mutant Yeast
Performing Gene Therapy on Mutant Yeast
Setting up Yeast Matings
Screening Household Products for Carcinogens
Assignments There are six problem sets for this course. Of the six graded problem sets, the lowest grade is dropped in calculating your final grade (see below). The last problem set, Problem Set 7, will not be graded, however, the material on this problem set will be covered on the Final Exam. Although you may engage in general discussions of problems, sharing of answers is a violation of the trust placed in all students in the class, each of whom is entrusted with producing her/his own set of answers. Students who copy problem set answers or allow their problem sets to be copied may receive a 0 for all the Problem Sets (and thus lose 20% of the grade). Completed problem sets must be put in the appropriate TA's box in the wooden cart by the due date/time. Note: Problem sets will not be accepted late and will be scored ZERO points if not turned in on time. Exams Three quizzes and a final exam are given in this course. The quizzes are given during the term and a comprehensive final (worth 2 quizzes), given during finals week. Each of the term quizzes will take place in at least two locations, on the dates listed in the syllabus. See Quiz handouts for room assignments. The lowest letter grade score of the five (the 3 quizzes plus the final worth 2 quizzes) will be dropped when calculating your overall grade. Because we drop the lowest score, there will be no make-up quizzes and no conflict quizzes given for any reason. If you miss a term quiz, it will be the score that is dropped. The Final Exam is a 3-hour, cumulative exam, covering the entirety of the course. The score on the final exam will be halved and each half counts as a quiz score when calculating your grade. The final represents two of the five quiz scores and must be taken, otherwise you lose 20% of your grade. If your score on the final is your lowest grade then one of the halves will be dropped. The date, time, and location of the final will be announced as soon as this information is available. A conflict final exam may be scheduled by the registrar for students with legitimate exam conflicts. Quiz Review Sessions will be held prior to each quiz -- the dates, locations and times of the reviews will be announced during the term. Any quizzes, exams, or problem sets that are not picked up by the end of the term will be disposed of. Grades
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閱讀作業包括線上麻省理工學院生物超文本書籍的章節，大量科技文章，課堂講義，線上資源和必讀材料上的章節。
Reading assignments include sections from the online MIT Biology Hypertextbook, numerous scientific articles, class handouts, online resources, and sections from the required text. Freeman, Scott. 《生物科學》，Upper Saddle River, NJ: Prentice Hall, 2002. ISBN: 0130819239。
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復習的問題涵蓋了相應課時討論的內容。
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| 測驗1(PDF) Quiz 1 (PDF) |
測驗1(PDF) Quiz 1 (PDF) |
| 測驗2(PDF) Quiz 2 (PDF) |
測驗2(PDF) Quiz 2 (PDF) |
| 測驗3(PDF) Quiz 3 (PDF) |
測驗3 (PDF) Quiz 3 (PDF) |
可下載的測驗練習在各自的檔後面有答案。測驗以答案檔的方式提供。
The downloadable practice exams include solutions at the end of each respective file. Exams are provided as solutions files.
期末考試是3個小時的綜合測驗，內容涵蓋整個課程。
The Final Exam is a 3-hour, cumulative exam, covering the entirety of the course.
期末考試練習(PDF)
Practice final exam (PDF)
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2003年秋季作業
課堂講義
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對「課程7.012：生物學導論」這門課有興趣的教育家、學生和自學者們，歡迎來和其他應用這個教材學習或教課的人在這個討論群組上互動。
這個服務是由麻省理工學院開放式課程提供，由猶他州立大學教育科技系的「開放持續學習機會研究群」所管理。世界各地的獨立學員可以互相連繫、協同合作、組織學習小組，及就利用麻省理工「開放式課程網頁」教材資源於他們正規或非正規教育學習時得到支援。 「開放式學習支援網」(Open Learning Support, 簡稱OLS)是一個著眼著眼於建立「社群軟體」的研究計劃，讓非正規學習社群利用現存公開的教材而組織起來。OLS基本前提是完整的教育機會必須讓使用者 能夠與能解答其問題或提供支援的其他人建立起溝通管道。贊助者一般只能提供免費開放的網頁教材，但很難提供這樣的社群管道。社群支援必須由其他使用者提 供。因此，OLS是： 在麻省理工「開放式課程網頁」以外獨立運作的 需要使用者註冊並登入才能參與的 並不頒授任何學位或文憑的計劃 不提供與麻省理工或猶他州立大學教職人員直接連繫的管道 馬上來本課程《7.012 生物學導論》的討論群組看看吧。「開放式學習支援網」是由The William and Flora Hewlett 基金會贊助提供。 |
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需要RealOneTM播放器軟體來運行本課程網站上的.rm文件。 RAW = Robert A. Weinberg教授
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