MIT OpenCourseWare

20.430J / 2.795J / 6.561J / 10.539J / HST.544J Fields, Forces, and Flows in Biological Systems (BE.430J), Fall 2004

Diagram of charge distribution on thrombin.
Glycoprotein Ibα (GpIbα), a receptor on the surface of platelets in the blood, binds to several signaling molecules including thrombin, an enzyme released from damaged tissue that is required for blood clotting. This diagram shows the charge distribution on the surface of thrombin (red is negative, blue is positive). The GpIba receptor is shown in green with the surface rendered transparent. (Image courtesy of Lawrence Berkeley National Laboratory.)

課程重點

This course features a complete set of lecture notes.

課程描述

This course covers the following topics: conduction, diffusion, convection in electrolytes; fields in heterogeneous media; electrical double layers; Maxwell stress tensor and electrical forces in physiological systems; and fluid and solid continua: equations of motion useful for porous, hydrated biological tissues. Case studies considered include membrane transport; electrode interfaces; electrical, mechanical, and chemical transduction in tissues; electrophoretic and electroosmotic flows; diffusion/reaction; and ECG. The course also examines electromechanical and physicochemical interactions in biomaterials and cells; orthopaedic, cardiovascular, and other clinical examples.

師資

講師:
Prof. Alan Grodzinsky
Prof. Douglas Lauffenburger

上課時數

教師授課:
每週2節
每節1.5小時

複習課程:
每週1節
30 minutes / session

程度

研究所

回應

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原文聲明