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燈號說明

審定:無
翻譯:林其昌(簡介並寄信)
編輯:邱富敏(簡介並寄信)

課程描述

這門課程是介紹以應用於組織工程學中設計醫療植體、人工器官和基質為主的材料科學和細胞生物學。內容包括生醫材料表面特性檢測和蛋白質吸附於生醫材料表面的分析。分子和細胞與生醫材料的交互作用並以單元細胞過程來進行分析,譬如基質合成、降解和收縮。同時包括創傷癒合和植入不同器官後組織重塑之作用機制。其它領域則包括組織和器官再生;植體和義肢根據生醫材料與組織交互作用的設計;及藉由參考例案以比較分析完整原型,生物可分解型和生物可置換型等各種植體。並會探討組織和器官之生理功能恢復的評斷標準。

書本

Yannas, I. V. 《成人組織和器官的再生》. New York: Springer, 2001. ISBN: 0387952144.

先修課號

3.091或5.11或5.111或5.112

2.005或5.60

7.012或 7.013


Course Description

This course is an introduction to principles of materials science and cell biology underlying the design of medical implants, artificial organs, and matrices for tissue engineering. Topics include methods for biomaterials surface characterization and analysis of protein adsorption on biomaterials. Molecular and cellular interactions with biomaterials are analyzed in terms of unit cell processes, such as matrix synthesis, degradation, and contraction. It also covers mechanisms underlying wound healing and tissue remodeling following implantation in various organs. Other areas include tissue and organ regeneration; design of implants and prostheses based on control of biomaterials-tissue interactions; comparative analysis of intact, biodegradable, and bioreplaceable implants by reference to case studies. Also addressed are criteria for restoration of physiological function for tissues and organs.

Text

Yannas, I. V. Tissue and Organ Regeneration in Adults. New York: Springer, 2001. ISBN: 0387952144.

Prerequisites

3.091 or 5.11 or 5.111 or 5.112

2.005 or 5.60

7.012 or 7.013