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課程單元 閱讀資料
1 大腦行為研究之歷史及目標(1) Mackay著,《決定論的瓦解─新科學家 第二期》,1970年,第26-26頁 [1]
2 大腦行為研究之歷史及目標(2) Rosenzweig著,《生物心理學 第一章:機會與展望》第1-21頁 {2, 3}
3 大腦行為研究之歷史及目標(3)

Gazzaniga著,《認知神經科學的方法 第三章b節》,第75-120頁{3, 10-13, 20-38}

Gazzaniga著,《認知神經科學之簡史 第一章》第1-21頁 {3}

4 目標:當代理論及方法

Rosenzweig著,《功能性神經解剖學 第二章》,第25-56頁 {4-5, 9-13}

Gazzaniga著,《認知的基層物質 第二章a節》第23-28頁 {4-5}

Gazzaniga著,《認知神經科學的方法 第三章a節》第69-74頁 {4-5}

Nauta 與 Feirtag著,《神經元 第二章;些許數目》第12-38頁 {4-6}

Nauta 與 Feirtag著,《解剖學上的區隔 第三章》第39-49頁 {4-5, 7-13}

5

神經細胞內之基礎細胞機制表現

Rosenzweig著,《神經生理學 第三章:傳導、傳遞與神經訊號之整合》第55-85頁 {5-7}

Rosenzweig著,《分子生物學 附錄:基本概念與重要技巧》第A-1 到 A-8

Rosenzweig著,《精神病藥物學 第四章:神經傳導體、藥物與行為》第87-115頁 {5-7}

Rosenzweig著,《荷爾蒙與行為 第五章》第 117-146頁 {5, 11}

Gazzaniga著,《認知的基層物質 第二章b節》第28-44. {5-6}

6 神經內傳導及神經間傳遞 Rosenzweig著,《感官處理與碰觸…等基本原則 第八章》第213-235頁 {6, 10-11}
7 突觸傳遞(總結)與神經解剖學技術

Rosenzweig著,《大腦的進化與行為 第六章》第149-175頁 {7-8}

Nauta與 Feirtag著,《早期的種系發展史 第一章;偉大的調節網絡》第1-11頁 {7-8}

Nauta 與 Feirtag著,《軸突的描繪 第四章》第50-61頁 {7}



*編者註:軸突(axon)乃為神經傳導的線路,負責將樹突(dendrite)接收刺激的訊號傳達到終端(terminal),終端則會將此神經細胞的刺激訊號傳達到下一個神經細胞。

8 *「中樞神經系統」及其演化之導論
*刺激─反應(Stimulation-Response)理論對比內生性之角色
9

*演化小語
*原始哺乳類腦部簡介
*反射及小腦路徑

Nauta 與 Feirtag著,《第五章至第十章a節》第63-143頁 {9-14}

Gazzaniga著,《認知的基層物質 第二章c節》第44-68頁 {9-10}

Wolpert著,《演化 第十四章》第183-197頁 {9, 16}

10 *胚胎腦部次級細解
*傳導路徑:蹄系路徑
*橫斷效應與失聯絡現象的概念
11 *橫斷解剖、功能、物種差異
*新皮質、新蹄系及皮質脊髓路徑
12 *脊髓神經解剖
*自主神經系統
*奧圖羅威的發現
13 後腦及中腦描繪
14 中腦及前腦描繪
15 *神經解剖複習
*神經發展簡介

Rosenzweig著,《大腦的壽命發展與行為 第七章》第177-210頁 {15-18}

Wolpert著,《外型的塑造 第二章》第11-28頁 {15-16}

Wolpert著,《形式的組成 第三章》,第31-58頁 {15-16}

16 *神經遷移介紹及種類
*各階段軸突之生長簡介

Wolpert著,《幫大腦上發條 第八章》第119-133頁 {16-17}

Wolpert著,《發展的規劃 第十五章》第199-203頁 {16-17}

17

軸突生長:發展因素

18 *軸突生長之發展因素
*鄰近神經的側支及真實神經重生
19 運動系統(1):脊髓神經組織、退縮反射

Bizzi, E等著,《青蛙的脊隨神經中運動行為的模件組織》,神經科學的潮流,第18期,1995年,第442-446頁 {19}

Rosenzweig著,《動態與行動(第一部份) 第十一章a節》第323-338頁 {19-20}

Gazzaniga著,《運動神經的控制 第十章》第371-421頁 {19-21}

Nauta 與 Feirtag著,《運動系統第七章a節:局部的運動器官》第91-94頁 {19-20}

20 運動系統(2):伸張反射、脊髓可塑性 Rosenzweig著,《動態與行動(第二部份) 第十一章》第338-359頁 {20-21}
21 *運動系統(3):下行路徑
*羅倫斯及古柏實驗(影片)

Klawans, Harold L著,《依然微笑(威爾森氏症) 第二章》,進一步的臨床神經學─牛頓的瘋狂,1990年,第19-29頁 {21}

Klawans, Harold L著,《蜥蝪(帕金氏症) 第五章》進一步的臨床神經學─牛頓的瘋狂,1990年,第53-65頁 {21}

Klawans, Harold L著,《危機下的主題(亨丁頓舞蹈症) 第十五章》,進一步的臨床神經學─牛頓的瘋狂,1990年,第140-150頁 {21}

Klawans, Harold L著,《她原本能夠徹夜跳著舞(亨丁頓舞蹈症) 第十六章》進一步的臨床神經學─牛頓的瘋狂,1990年,第151-157頁 {21}

Klawans, Harold L著,《雙眼飛舞的女孩(血清素引發的肌陣攣)第十八章》第165-173頁 {21}

期中考
22 運動控制中之規律性輸出及時機

Rosenzweig著,《振動的迴路….》第80-81頁,第346-349頁 {23}

Rosenzweig著,《生物的律動、睡眠與造夢 第十四章》第431-465頁 {23-24}

Rosenzweig、Dowling與John E著,《規律的運動行為之控制 第十章》神經元與神經網絡─神經科學之導論,哈佛大學出版社,1992年,第217-237頁 {23-24}

23 續:呼吸機制與活動/睡眠之律動
Activity and sleep rhythms
24 內容為Wm Dement、安眠藥作用等等的「睡眠及清醒」影片欣賞
25 習慣與創新反應

Rosenzweig著,《感官處理的一般原則 第八章a節》第213-235頁 (複習先前之閱讀) {26}

26 視覺系統(1):神經解剖、剝落效應

Rosenzweig著,《視覺 第十章》 第281-321頁{26-30}

27 視覺系統(2):剝落效應

Gazzaniga著,《認知與解碼 第四章》第121-161頁 {26, 29-33}

28 *視覺系統(3):剝落效應,為視網膜生理學做出結論
29

*視覺系統(4):視網膜、外側膝狀體、及其他(參照課文閱讀部分)

Gazzaniga著,《更高級的感官功能 第五章》第163-205頁 {30-33}
30 *視覺系統總結
*聽覺系統
Rosenzweig著,《聽力,內耳感官….第九章》第247-269頁 {31-32}
31 聽覺系統總結
32 疼痛及中腦中央灰質區

Rosenzweig著,《觸覺與疼痛 第八章》 第213-245頁 {33}

講義:兩種激發系統 (邊緣系統與非邊緣系統) {33}

Rosenzweig著,《情感、積極與壓力 第十五章》第469-501頁 {33, 34-36}

Rosenzweig著,《嚐與聞 第九章》第269-279頁 {33}

Rosenzweig著,《性別 第十二章 第363-398頁》亦見第139-140頁{33-36}

33 下視丘與飲食 Rosenzweig著《體內平衡 第十三章:內部狀態的積極管制》第399-432頁 {34-36}
34 驅力對比回饋;競爭行為及神經倫理學
35 嶄新理論:生動機器人
人造情感的人格及行為選擇

Rosenzweig著,《學習與記憶 第十七章:生物透視法》第537-570頁 {36-38}

Rosenzweig著,《學習與記憶 第十八章:神經機制》第571-605頁 {36-38}

Rosenzweig著,《語言與認知 第十九章》第607-642 {36-38}

Rosenzweig著,《事後:千變萬化的大腦》第643-651 {36-38}

Gazzaniga著,第7, 8, 9, 11章 {36-38}

36 較高層功能:人類本質和神經科學 Rosenzweig著《精神病理學 第十六章:行為錯亂下的生物基礎》第503-534頁 {37-38}
37 人類本質和神經科學,結論
38

複習、問答時間

Rosenzweig著,《專業術語,G-1 到 G-26》(學生們必須在學期末前,了解絕大多數的詞彙)
期末考

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Refer to the readings page for complete citations.


課程單元 閱讀資料
1 History and goals of brain-behavior studies, 1 Mackay, "The bankruptcy of Determinism. New Scientist, 2", (1970), pp. 24-26. [1]
2 History and goals, 2 Rosenzweig, "ch. 1, Biological psychology: scope and outlook", pp. 1-21. {2, 3}
3 History and goals, 3

Gazzaniga, "ch. 3b, The methods of cognitive neuroscience", pp. 75-120. {3, 10-13, 20-38}

Gazzaniga, "ch. 1, A brief history of cognitive neuroscience", pp. 1-21. {3}

4 Goals: current theory and methods

Rosenzweig, "ch. 2, Functional neuroanatomy", pp. 25-56. {4-5, 9-13}

Gazzaniga, "ch. 2a, The substrates of cognition", pp. 23-28. {4-5}

Gazzaniga, "ch. 3a, The methods of cognitive neuroscience", pp. 69-74. {4-5}

Nauta & Feirtag, "ch. 2, The neuron; some numbers", pp. 12-38. {4-6}

Nauta & Feirtag, "ch. 3, Anatomical divisions", pp. 39-49.{4-5, 7-13}

5

Primitive cellular mechanisms
Expression in neurons

Rosenzweig, "ch. 3, Neurophysiology: conduction, transmission, and integration of neural signals", pp.55-85. {5-7}

Rosenzweig, "Appendix. Molecular biology: basic concepts and important techniques", pp. A-1 to A-8.

Rosenzweig, "ch.4, Psychopharmacology: neurotransmitters, drugs, and behavior", pp.87-115. {5-7}

Rosenzweig, "ch. 5, Hormones and behavior", pp. 117-146. {5, 11}

Gazzaniga, "ch. 2b, The substrates of cognition", pp. 28-44. {5-6}

6 Neuronal conduction and transmission Rosenzweig, "ch. 8, General principles of sensory processing, touch…", pp. 213-235. {6, 10-11}
7 Transmission at synapses (concluded)
Neuroanatomical techniques

Rosenzweig, "ch. 6, Evolution of brain and behavior", pp. 149-175. {7-8}

Nauta & Feirtag, "ch. 1, Early phylogeny; the great intermediate net", pp. 1-11. {7-8}

Nauta & Feirtag, "ch. 4, Axon tracing", pp. 50-61. {7}

8 Intro to “CNS”and its evolution
S-R theory vs role of endogenous activity
9

Notes on evolution
Primitive mammalian brain outline
Reflex and Cerebellar channels

Nauta & Feirtag, "ch. 5-10a", pp. 63-143. {9-14}

Gazzaniga, "ch. 2c, The substrates of cognition", pp. 44-68. {9-10}

Wolpert, "ch. 14, Evolution", pp. 183-197. {9, 16}

10 Subdivisions of embryonic brain
Channels of conduction: lemniscal channels
Transection effects and diaschisis concept
11 Transections, functions, species differences
Neocortex, neo-lemniscus, and corticospinal pathways
12 Spinal cord anatomy
Autonomic N.S.
Otto Loewi’s discovery
13 Hindbrain and midbrain pictures
14 Midbrain and forebrain pictures
15 Neuroanatomy review. Intro to development

Rosenzweig, "ch. 7, Life-span development of the brain and behavior", pp. 177-210. {15-18}

Wolpert, "ch. 2, Molding of form", pp. 11-28. {15-16}

Wolpert, "ch. 3, Pattern formation", pp. 31-58. {15-16}

16 Migration – types
Axon growth stages introduced

Wolpert, "ch. 8, Wiring the brain", pp. 119-133. {16-17}

Wolpert, "ch. 15, A programme for development", pp. 199-203. {16-17}

17

Axon growth: developmental factors

18 Developmental factors
Collateral sprouting and true regeneration
19 Motor 1: spinal cord organization, withdrawal reflex

Bizzi, E. et al., "Modular organization of motor behavior in the frog’s spinal cord", Trends in Neuroscience, 18, (1995) pp.442-446. {19}

Rosenzweig, "ch 11a, Movements and actions (part 1)", pp. 323-338. {19-20}

Gazzaniga, "ch. 10, Motor control", pp. 371-421. {19-21}

Nauta & Feirtag, "ch. 7a, ... The motor system: Local motor apparatuses", pp. 91-94. {19-20}

20 Motor 2: stretch reflexes
Spinal plasticity
Rosenzweig, "ch. 11, Movements and actions (part 2)", pp.338-359. {20-21}
21 Motor 3: descending pathways
Lawrence and Kuypers experiments (film)

Klawans, Harold L, "Ch.2, Still smiling (Wilson’s disease)", Newton’s madness, further tales of clinical neurology, (1990), pp. 19-29. {21}

Klawans, Harold L, "Ch. 5, The lizard (Parkinson’s disease)", Newton’s madness, further tales of clinical neurology, (1990), pp. 53-65. {21}

Klawans, Harold L, "Ch. 15, The subject at risk (Huntington’s chorea)", Newton’s madness, further tales of clinical neurology, (1990), pp. 140-150. {21}

Klawans, Harold L, "Ch. 16, She could have danced all night (Huntington’s chorea)", Newton’s madness, further tales of clinical neurology, (1990), pp. 151-157. {21}

Klawans, Harold L, "Ch. 18, The girl with dancing eyes (serotonin-induced myoclonus)", pp. 165-173. {21}

MIDTERM EXAM
22 Rhythmic output and timing in motor control

Rosenzweig, "Oscillatory circuits...", p. 80-81, pp. 346-349. {23}

Rosenzweig, "ch. 14, Biological rhythms, sleep, and dreaming", pp. 431-465. {23-24}

Rosenzweig, Dowling, John E., "ch. 10, Control of rhythmic motor behavior", Neuron and Networks, An Introduction to Neuroscience, Harvard Univ. Press, 1992, pp. 217-237. {23-24}

23 Continued: model of breathing mechanism
Activity and sleep rhythms
24 Sleep and waking
Video showing Wm Dement, narcoleptics, etc.
25 Habituation and novelty responses

Rosenzweig, "ch. 8a, General principles of sensory processing...", pp. 213-235 (review of previous reading). {26}

26 Visual system 1: neuroanatomy
Ablation effects

Rosenzweig, "ch.10, Vision...", pp. 281-321. {26-30}

27 Visual system 2: Ablation effects

Gazzaniga, "ch. 4, Perception and encoding", pp. 121-161. {26, 29-33}

28 Visual system 3: Ablations, concluded
Physiology of retina
29

Visual system 4: Retina, LGB, and further (ref. to readings)

Gazzaniga, "ch. 5, Higher perceptual functions", pp. 163-205. {30-33}
30 Visual system, concluded
Auditory system
Rosenzweig, "ch. 9, Hearing, vestibular sensation...", pp. 247-269. {31-32}
31 Audition concluded
32 Pain and the midbrain central gray area

Rosenzweig, "ch. 8, ...Touch and pain", pp. 213-245. {33}

Handout: two arousal systems (limbic and non-limbic). {33}

Rosenzweig, "ch. 15, Emotions, aggression, and stress", pp. 469-501. {33, 34-36}

Rosenzweig, "ch. 9, ...Taste and smell", Page 4 of 5 pp. 269-279. {33}

Rosenzweig, "ch. 12, Sex, pp 363-398", also 139-140. {33-36}

33 Hypothalamus and feeding. Rosenzweig, "ch. 13, Homeostasis: active regulation of internal states", pp 399-432. {34-36}
34 Drive vs. reward; agonistic behavior and neuroethology
35 New theory: animats
Affective synthetic characters and action selection

Rosenzweig, "ch. 17, Learning and memory: biological perspectives", pp. 537-570. {36-38}

Rosenzweig, "ch. 18, Learning and memory: neural mechanisms", pp. 571-605. {36-38}

Rosenzweig, "ch. 19, Language and cognition", pp. 607-642. {36-38}

Rosenzweig, "Afterward: The ever-changing brain", pp. 643-651. {36-38}

Gazzaniga, ch. 7, 8, 9, 11. {36-38}

36 Higher functions: human nature and neuroscience Rosenzweig, "ch.16, Psychopathology: biological bases of behavior disorders", pp.503-534. {37-38}
37 Human nature and neuroscience, conclusion
38

Review
Question-and-answer sessions

Rosenzweig: "Glossary, G-1 to G-26". (Students should know most of these terms by the end of the semester).
FINAL EXAM

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