麻省理工學院「開放式課程網頁」 | 腦與認知科學 | 9.97 2003一月(自由活動月)課程:神經解剖學導論 | 課堂講稿 MIT OpenCourseWare » 進階搜尋  課程首頁 教學大綱 教學時程 課堂講稿 測驗 研習資料 相關資源精神分裂症憂鬱症神經退化的疾病阿茲海默氏症阿茲海默氏症類別的老邁痴呆診斷為無法完成日常生活活動的記憶損失一個由於老年人口而發現的「疾病」巨觀解剖:高等皮質的退化微觀解剖: 澱粉體小板與糾結約五成早期阿茲海默氏症患者有澱粉體(amyloid)前驅蛋白的變異路•蓋里格氏病/肌萎縮性脊髓側索硬化基底核的疾病亨丁頓式症巴金森式症神經可塑性與疾病

去傳入性的疾病
    多發硬化症幻肢疼痛/中央疼痛腦血管的疾病中風高血壓?可思考的議題偏頭痛疾病與神經機動性特別與語言有關的學習缺損癲癇-杜思妥也夫司基與尼爾楊(譯註:為兩個罹患癲癇仍然非常有創作力的名人,前者為作家,後者為搖滾樂手。)、所羅在通往大馬士革之途變成保羅(譯註:為著名的聖經故事,所羅在通往大馬士革之途經歷了耶穌的顯靈,但被認為可能是癲癇發作的症狀之一 -- 轉述自授課教授Moore。)、過度可激發性導致興奮波擴散到整個大腦結構與功能的關聯

    「小腦的病人」運動步履蹣跚精神病症音調區辨語言能力觸覺知覺缺損非瑣細地區位化

    神經傳導物質系統的缺損(精神分裂症, 憂鬱症)
    幻肢

    阿茲海默氏症
    The topics covered in this course are delineated below.
    Disease and the Brain
    Why are we interested in the brain? Why is there a whole major on this?
    Diseases List 'Off the top of My Head'
    Diseases of NT SystemsSchizophreniaDepressionDiseases of Neural DegenerationAlzheimer'sSenile Dementia of the Alzheimer's TypeDiagnosed as memory loss with inability to complete activities of daily livingA "discovered" disease due to an aging populationMacroanatomy: Degeneration of higher corticesMicroanatomy: Amyloid plaques and tanglesAbout 50% of those with early AD have been found to have mutations in the amyloid precursor proteinLou Gehrig/ALSDiseases of the Basal GangliaHuntington'sParkinson'sPlasticity and Disease

    Diseases of Deafferentation
      Multiple SclerosisPhantom pain/central painDiseases of VasculatureStrokeHigh blood pressure? (Something to think about)MigraineDiseases and Neural DynamicsLanguage Specific Learning DeficitEpilepsy-Dostoyevsky to Neil Young; Saul becoming Paul on the road to Damascus; hyper-excitability leading to spreading waves of excitation in the brain.Association of Structure and Function

      "Cerebellar Patient"MotorStumbling gatePsychiatric disordersPitch discriminationLanguage abilityTactile perceptionDeficits are not Trivially Localizationist

      Deficits of NT systems (depression, schizophrenia)
      Phantom Limb

      Alzheimer's
      MIT Home
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