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翻譯:鄭宇(簡介並寄信)
編輯:朱學(簡介並寄信)

這門課程需要以下課本,它們是參考以下表格中羅列的閱讀日程。Shortliffe, E. H., L. E. Perreault, G. Wiederhold, and L. M. Fagan 醫學情報:電腦在衛生健康和生物醫學中的應用,第二版,. Springer, 2001
The following text is required for the course and is referenced in the calendar of readings listed in the table below. Shortliffe, E. H., L. E. Perreault, G. Wiederhold, and L. M. Fagan. Medical Informatics: Computer Applications in Health Care and Biomedicine. 2nd Edition. Springer, 2001.


課程單元 閱讀資料
1 介紹:現代醫學和醫學實踐性質
Introduction: Nature of Modern Medicine and Medical Practice
閱讀肖特堣猁熔臚@和第二章
Read Chapters 1 & 2 of Shortliffe.
2 醫學資料性質:是和不是的地方
Nature of Medical Data: Where it is and Where it is Not
閱讀肖特堣猁熔臚E和第十章
Read Chapters 9 & 10 of Shortliffe.
3 醫學基因組學:生物資訊學的核心
Genomics in Medicine: Centrality of Bioinformatics

〈人類基因組的初始序列和分析〉國際人類基因序列協會,409 (2001):Macmillan Magazines Ltd. 409 (2001): Macmillan Magazines Ltd
"Initial Sequencing and Analysis of the Human Genome." International Human Genome Sequencing Consortium, 409 (2001): Macmillan Magazines Ltd.

Chakravarti, Aravinda.〈人口遺傳學-序列外的認知〉自然遺傳學增刊21 (Jan 1999)俄亥俄州:凱斯西儲大學藥學院遺傳學系和人類遺傳學中心和美國城市醫學院.
Chakravarti, Aravinda. "Population Genetics — Making Sense Out of Sequence." Nature Genetics Supplement 21 (Jan 1999): Ohio: Department of Genetics and Center for Human Genetics, Case Western Reserve University School of Medicine and University Hospitals of Cleveland.

Brown, Patrick O., and David Botstein〈和DNA基因組探索染色體新世界〉 自然遺傳學增刊 21 (Jan 1999):斯坦福,加利福尼亞:生化遺傳學系,和霍華德休斯醫學研究所,斯坦福大學藥學院
Brown, Patrick O., and David Botstein. "Exploring the New World of the Genome with DNA Microarrays." Nature Genetics Supplement 21 (Jan 1999):
Stanford, California: Departments of Biochemistry and Genetics, and the Howard Hughes Medical Institute, StanfordUniversitySchoolof Medicine.

〈用基因運算式鑒別擴散巨大B細胞淋巴瘤的不同類型〉 Nature 403 (3 Feb. 2000): Macmillan Magazines Ltd.
"Distinct Types of Diffuse Large B-cell Lymphoma Identified by Gene Expression Profiling." Nature 403 (3 Feb. 2000): Macmillan Magazines Ltd.

4 病人的鑒別
Patient Identification
Fellegi, Ivan P., and Allen B. Sunter.“一個記錄聯鎖的理論“美國統計學會期刊64 (328) (Dec 1969): 1183-1210.
Fellegi, Ivan P., and Allen B. Sunter. "A Theory for Record Linkage." Journal of American Statistical Association 64 (328) (Dec 1969): 1183-1210.
5 反生物恐怖主義
Countering Bioterrorism
肖特堣猁熔臚Q一章
Chapter 11 of Shortliffe.
6 流程,決策支援和資料集
Workflow, Decision Support and Data Gathering

〈流程分析和循證醫學:醫院資訊系統中的綜合知識功能〉德國:門斯特大學
Mueller, Ganslandt, Frankewitsch, Krieglstein, Senninger, and Prokosch. "Workflow Analysis and Evidence-Based Medicine: Towards Integration of Knowledge-Based Functions in Hospital Information Systems." Germany: University of Muenster.

Coiera, Enrico. 〈臨床交流: 一個新的資訊學範例." Jamia (1996): 英國.
Coiera, Enrico
. "Clinical Communication: A New Informatics Paradigm." Jamia (1996): UK.

Coiera, Enrico〈當交談勝過計算的時候〉 Jamia (14 Jan. 2000): 華盛頓.
Coiera, Enrico. "When Conversation is Better than Computation." Jamia (14 Jan. 2000): Washington DC.

Kohane, Isaac S., Philip Greenspun, James Fackler, Christopher Cimino, and Peter Szolovits. 〈通過世界互聯網建立國家電子醫學記錄系統的技術應用〉 美國醫學資訊學協會期刊 3 (3) (May/Jun 1996).
Kohane, Isaac S., Philip Greenspun, James Fackler, Christopher Cimino, and Peter Szolovits. "Application of Technology in Building National Electronic-Medical Record Systems via the World Wide Web." Journal of the American Medical Informatics Association 3 (3) (May/Jun 1996).

7 企業的計算支持
Computing Support for the Enterprise
8 診斷,標準,編碼
Diagnosis, Standards, Codification
肖特堣猁熔臚說A十二和十四章
Chapters 6, 12 and 14 of Shortliffe.
9 患者資料的機密性和安全
Patient Data Confidentiality and Security

肖特堣猁熔臚C章
Chapter 7 of Shortliffe.

Barrows, Randolph. C. Jr., Paul D. Clayton. 〈隱私機密性和 EMR.〉 美國醫學資訊學協會期刊3 (2) (Mar/Apr 1996).
Barrows, Randolph. C. Jr., Paul D. Clayton. "Privacy Confidentiality and EMR." Journal of the American Medical Informatics Association 3 (2) (Mar/Apr 1996).

選擇:
Optional


  • 為了記錄,保護電子健康資訊.華盛頓 : 國家研究院出版, 1997.For the Record. Protecting Electronic Health Information. Washington D.C. : National Academy Press, 1997.
10 衛生保健中減少異變性
Decreasing Variability in Health Care
11 電腦化的醫生命令輸入:使用技術提高患者安全性
Computerized Physician Order Entry: Using Technology To Improve Patient Safety
12 為了提高質量,集成、資料共用或醫學資料
Integration and Data Sharing or Medical Data for Quality Improvement
13 遠端醫學
Telemedicine
肖特堣猁熔臚Q四章
Chapter 14 of Shortliffe.
14 基因組醫學I:在後基因組時代的人類遺傳學
Genomic Medicine I: Population Genetics in the Post Genomic Era

Lander, Eric S.〈希望的排列〉自然遺傳學附錄21 (1999): 劍橋, 麻塞諸塞:美國公司
Lander, Eric S. "Array of hope." Nature Genetics Supplement 21 (1999): Cambridge, Massachusetts: America Inc.

------.,和. Nicholas J. Schork.〈複雜特性的基因剖析〉科學,新叢書265 (5181) (30 Sep. 1994): 2037-2048.
------., and Nicholas J. Schork. "Genetic Dissection of Complex Traits." Science, New Series, 265 (5181) (30 Sep. 1994): 2037-2048.

〈大規模人類基因組中單核˙藻h態性的基因型的鑒定,映射,和定型〉 科學280 (15 May 1998): 1077.
"Large-Scale Identification, Mapping, and Genotyping of Single-Nucleotide Polymorphisms in the Human Genome." Science 280 (15 May 1998): 1077.
http://www.sciencemag.org

15 基因組醫學II:表達譜,基因聚類和距離度量
Genomic Medicine II: Expression Arrays, Gene Clustering and Distance Metrics
Michael, P. S. Brown, William Noble Grundy, David Lin, Nello Cristianini, Charles Walsh Sugnet, Terence S. Furey, Manuel Ares, Jr., and David Haussler.“採用支持向量的機器進行微陣列基因表達資料的知識基礎上的分析〉
Michael, P. S. Brown, William Noble Grundy, David Lin, Nello Cristianini, Charles Walsh Sugnet, Terence S. Furey, Manuel Ares, Jr., and David Haussler. "Knowledge-based Analysis of Microarray Gene Expression Data by Using Support Vector Machines." PNAS 97 (1) (4 Jan. 2000): 262-267.
16 決策分析和決策支持
Decision Analysis and Decision Support

肖特堣猁熔臚Q五和十六章
Chapters 15 and 16 of Shortliffe.

Szolovits, P.〈醫學資訊學中的不確定和決定〉醫學中的資訊學方法34 (1995): 111–21.
Szolovits, P. "Uncertainty and Decisions in Medical Informatics." Methods of Information in Medicine 34 (1995): 111–21.

17 功能基因組中獲取因果關係
Getting to Causality in Functional Genomics

〈人成纖維細胞血清應答中的轉錄程式〉科學 283 (1 Jan. 1999).
"The Transcriptional Program in the Response of Human Fibroblasts to Serum." Science 283 (1 Jan. 1999).
www.sciencemag.org

Ramoni, Marco F., Paola Sebastiani, and Isaac S. Kohane.〈基因表達動力學的集群分析〉PNAS. Edited by Louis M. Kunkel.
Ramoni, Marco F., Paola Sebastiani, and Isaac S. Kohane. "Cluster Analysis of Gene Expression Dynamics." PNAS. Edited by Louis M. Kunkel.

18 高級專家系統
Advanced Expert Systems
肖特堣猁熔12和13章
Chapters 12 and 13 of Shortliffe.
19 患者監控
Patient Monitoring
20 基因組醫學III:基因組學介紹
Genomic Medicine III: Introduction to Genomics
21 基因組醫學IV:連接基因型和表現型
Genomic Medicine IV: Linking Genotypes and Phenotypes
22 基因組醫學V:逆向工程學
Genomic Medicine V: Reverse Engineering
佐坦:〈大規模平行生物學的危機和承諾〉基因網路分析 第5章,2002.pp.23
Zoltan. "The Perils and Promises of Massively Parallel Biology." Chap. 5 in Genetic Network Analysis, 2002: pp. 23.
23 學生報告
Student Presentations
24 學生報告
Student Presentations
25 學生報告
Student Presentations
26 學生報告
Student Presentations

 
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